Science and clinic

Publications

Studies on CARDIOLAB, REOCOM, NEUROCOM and SPIROCOM systems.

Scientific papers and an ECG strip

The diagnostic systems are backed by clinical studies, dissertations and 30 years of use.

  • Vegetology HRV analysis for adaptation assessment.
  • Hemodynamics Endothelial function and vascular tone.
  • Neurophysiology EEG patterns and neurodynamics.
  • Pulmonology COPD monitoring and respiratory function.

Some links go to external repositories; full text depends on the publisher. Without a translation, the paper stays in the original language.

CardioLab - Electrocardiography and HRV

Equipment

Scientific Study: Effect of caffeine on heart rate variability in doxorubicin cardiomyopathy

Experimental study, 2025. In press. Analysis via CardioLab.

Hypodynamia and gonadectomy: impact on HRV parameters in experimental rats

Experimental Physiology Group, 2025. Pre-print. Research on adaptive capabilities.

Nazarenko V. I., Berestovskyi O. S., Moroz H. Z. Heart rate variability in COVID-19 patients with different levels of cardiovascular risk

Wiadomości Lekarskie, 2022, Vol. 75, Iss. 4, pp. 845-850. HRV study in COVID-19.

Source

Kudiy L. I., Varetska O. V., Kudiy S. V. Reliability of "Rytm" software for heart rate variability analysis

Journal of Physical Education and Sport, 2020, Vol. 20 (6), Art 427, pp. 3154-3160. "Rytm" SW validation.

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Kulbashna N. I., Polyakov A. S. Changes in the stress index of a passenger car driver when moving in a dense traffic flow

Transport Technologies, 2020. HRV study using CARDIOCOM.

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Kentesh O. P., Nemesh M. I. Functional state of the autonomic nervous system depending on the body composition

Wiadomości Lekarskie, 2018, Vol. 71, Iss. 2, pp. 312-316.

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Tymoshchuk O. V. Diagnosis of adaptation disorders in children with chronic gastroduodenitis based on HRV indicators

Child's Health, 2016, No. 7 (75). Autonomic status assessment.

Syvolap V. D. Electrocardiographic diagnostics and hemodynamic parameters in acute myocardial infarction

Zaporozhye Medical Journal, 2013, No. 2 (77), pp. 45-48.

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Syvolap V. V., Kyselov S. M., Apolikhin O. I. Structural-geometric and functional assessment of myocardium in patients with stage II hypertension

Zaporozhye Medical Journal, 2012, No. 1 (70), pp. 34-37. CardioLab application.

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Dovgan O. P. Spectral analysis of heart rate variability under different modes of artificial lung ventilation

Scientific Works of TNTU. Research using CARDIOCOM.

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Polyakov A. S. Automated processing of biomedical signals in cardiography

Collection of scientific papers. CARDIOCOM algorithm analysis.

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ReoCom - Rheography and Endothelial Function

Equipment

The D. Celermajer method and its capabilities in assessing endothelial function

Klin. inform. telemed., 2017, vol. 12, is. 13, pp. 64–69. DOI: 10.31071/kit2017.13.08

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Assessment of endothelial function from rheographic data

Klin. inform. telemed., 2018, vol. 13, is. 14, pp. 19–27. DOI: 10.31071/kit2018.14.02

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Assessment of endothelial function considering the operating point of endothelial regulation

Klin. inform. telemed., 2019, vol. 14, is. 15, pp. 74–87. DOI: 10.31071/kit2019.15.07

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Assessment of endothelial function under elevated patient pressure and medication

Klin. inform. telemed., 2021, vol. 16, is. 17, pp. 69–82. DOI: 10.31071/kit2021.17.06

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Pulse Wave Propagation Velocity and Assessment of Arterial Vessel Elasticity

Smart Technologies in Urban Engineering (STUE 2022). Lecture Notes in Networks and Systems, vol. 536. Springer, Cham. DOI: 10.1007/978-3-031-20141-7_6

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Evaluation of Endothelium Regulation of Vascular Tone

Smart Technologies in Urban Engineering (STUE 2022). Lecture Notes in Networks and Systems, vol. 536. Springer, Cham. DOI: 10.1007/978-3-031-20141-7_8

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Rheographic Evaluation of Endothelium Regulation of Vascular Tone

Smart Technologies in Urban Engineering (STUE 2023). Lecture Notes in Networks and Systems, vol. 807. Springer, Cham. DOI: 10.1007/978-3-031-46874-2_4

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Combination of Endothelium-Dependent and Endothelium-Independent Vasodilation Tests in the Assessment of Endothelial Function

Smart Technologies in Urban Engineering (STUE 2023). Lecture Notes in Networks and Systems, vol. 807. Springer, Cham. DOI: 10.1007/978-3-031-46874-2_5

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Experimental Study of the Rheographic Method for Assessing Endothelial Function

Smart Technologies in Urban Engineering (STUE 2024). Lecture Notes in Networks and Systems, vol. 1659. Springer, Cham. DOI: 10.1007/978-3-032-06832-3_6

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Noninvasive Assessment of Central Aortic Pressure

Smart Technologies in Urban Engineering (STUE 2024). Lecture Notes in Networks and Systems, vol. 1659. Springer, Cham. DOI: 10.1007/978-3-032-06832-3_5

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Rheography and Blood Pressure Measurement

Lighting Engineering & Power Engineering, 63(3), 75–81, 2024. DOI: 10.33042/2079-424X.2024.63.3.06

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Assessment of the state of the vascular system based on the results of rheographic measurements

Lighting Engineering & Power Engineering, 64(1), 125–137, 2025. DOI: 10.33042/2079-424X.2025.64.1.03

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Method of measuring carotid-femoral and aorto-femoral pulse wave velocity using rheography

Liky Ukrainy, 2016, No. 10 (206), pp. 22–32. DOI: 10.37987/19979894.2016.10(206).207664

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Comparative assessment of pulse wave velocity measurement by rheography and Doppler ultrasound

Heart and Vessels, 2016, No. 4, pp. 72–79.

Source

Assessment of blood filling of arterial vessels and blood supply to vascular regions by rheographic method

Research paper. XAI-Medica. (bibliographic details to be confirmed)

New approaches to assessing the vascular system from rheographic studies

Proc. XV Int. Conf. "New Information Technologies in Medicine, Biology, Pharmacology and Ecology" (IT+M&Ec`2007), Yalta-Gurzuf, 2007, pp. 355–357.

New approaches to assessing the vascular system from rheographic measurements

V Int. Symposium "Current Problems of Biophysical Medicine", Kyiv, 2007, pp. 158–159.

Assessment of the vascular system from rheographic studies

Herald of Epileptology, 2007, No. 1 (19-20), pp. 49–62.

Using the rheographic method to determine the blood pressure level

Medical Engineering, 2008, No. 3 (4), pp. 93–94.

Патент № 126286: Method for assessing the ankle-brachial index

Patent for invention, 14.09.2022.

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Патент № 126287: Method for determining peripheral venous pressure

Patent for invention, 14.09.2022.

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Патент № 122472: Method for assessing central aortic pressure

Patent for invention, 10.11.2020.

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Патент № 151684: Method for assessing the functional state of arterial endothelium

Patent for utility model, 31.08.2022.

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Патент № 130204: Method for determining arterial endothelial function

Patent for invention, 18.12.2025.

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Патент № 160285: Method for determining arterial endothelial function

Patent for utility model, 28.08.2025.

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Патент № 129815: Method for measuring blood pressure and arterial distensibility

Patent for invention, 06.08.2025.

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Патент № 129444: Method for measuring blood pressure

Patent for invention, 23.04.2025.

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Патент № 161146: Method for improving the accuracy of central aortic pressure assessment

Patent for utility model, 12.11.2025.

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Патент № 162517: Method for assessing and monitoring central aortic pressure

Patent for utility model, 02.04.2026.

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Патент № 159521: Method for assessing the ankle-brachial index

Patent for utility model, 12.06.2025.

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Патент № 1933395: Method for determining functional parameters of main arterial vessels of blood flow distribution

Invention application, 07.07.2026.

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Патент № 1933416: Method for determining functional parameters of main arterial vessels of blood flow distribution

Utility model application, 07.07.2026.

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Lutsyk N. Structural-geometric and functional assessment of the myocardium in patients with hypertension

Scientific Paper, TNTU 2021. Rheographic analysis application.

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Patent No. 121689: Method for assessing central aortic pressure

Registered in the State Patent Register of Ukraine, 10.07.2020.

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Patent No. 120800: Method for measuring blood pressure

Registered in the State Patent Register of Ukraine, 10.02.2020.

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Patent No. 118939: Method for assessing the function of arterial vessel endothelium

Registered in the State Patent Register of Ukraine, 25.03.2019.

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Study of endothelial regulation of vascular tone (Parts 1 and 2)

Methodological guide, 2014. XAI-Medica. Step-by-step guide.

Part 1Part 2

Fedorov A. A. Functional state of endothelium in patients with vasospastic angina

Journal of Cardiovascular Diseases, 2014. Clinical study.

Penelova Z. V. Features of psychophysiological reaction when using the "ReoCom-stress" complex

Zaporozhye Medical Journal, 2013, No. 4 (79).

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Blood pressure in symmetric vascular basins: rheographic assessment

Methodological article, 2012. Measurement protocol with ReoCom.

Read

Assessment of cerebral blood flow volumetric velocity (according to Paleev)

XAI-Medica Methodological guide, 2008. Kharkiv.

Read

Selection of informational parameters in rheographic assessment of endothelial function in a reactive hyperemia test

XAI-Medica Methodological Recommendations, 2007. Kharkiv.

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Pulse wave velocity and elastic properties of arterial vessels

Methodological development. Arterial stiffness assessment.

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Assessment of the vascular system based on rheographic measurement results

Scientific and methodological review. Data interpretation algorithms.

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New approaches to vascular system assessment based on rheographic studies

Methodological materials. Application in clinical practice.

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Rheographic assessment of peripheral circulation (Full archive)

XAI-Medica Collection. Methods and results.

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NeuroCom - Electroencephalography

Equipment

Distortion-free rejection of artifacts in EEG channel signals

Herald of Epileptology, 2011, No. 1 (35-36), pp. 36–52.

Computer EEG systems: yesterday and today

Med&Tech. Medical Engineering and Equipment, 2008, No. 3, pp. 20–22.

Using the Independent Component Analysis approach in computer EEG data processing

Proc. V Int. Symposium "Current Problems of Biophysical Medicine", Kyiv, 2007, pp. 160–161.

New options for improving coherent averaging of evoked potentials and source localization

Proc. All-Russian Conf. "Quantitative EEG and Neurotherapy", St. Petersburg, 2007, pp. 33–35.

Using Independent Component Analysis (ICA) to detect and remove artifacts in EEG channel signals

Proc. All-Russian Conf. "Quantitative EEG and Neurotherapy", St. Petersburg, 2007, pp. 36–38.

Solving the EEG inverse problem via decomposition into statistically independent components

Regional competition "Best Young Scientist of Kharkiv Region 2007".

Independent component decomposition to improve the quality of brain evoked potentials averaging

Proc. XXIX Int. Conf. "Lasers in Medicine and Biology", VII Vasiliev Readings, V. N. Karazin KhNU, 2008, pp. 212–213.

ICA technology and improved coherent averaging of evoked potential signals

Proc. Second All-Russian Conf. "Quantitative EEG and Neurotherapy", St. Petersburg, 2009, p. 51.

Using ICA to improve coherent averaging of evoked potentials and reject stimulus-locked artifacts

Proc. VI Int. Symposium "Current Problems of Biophysical Medicine", Kyiv, 2009, p. 93.

Using ICA technology for distortion-free artifact rejection in EEG channel signals

Proc. VI Int. Symposium "Current Problems of Biophysical Medicine", Kyiv, 2009, p. 92.

Distortion-free rejection of electroencephalographic artifacts

Proc. First All-Ukrainian Congress "Medical and Biological Informatics and Cybernetics", Kyiv, 2010, p. 202.

Spatial localization of evoked potential sources

Proc. First All-Ukrainian Congress "Medical and Biological Informatics and Cybernetics", Kyiv, 2010, p. 204.

Maruschak P., Lutsyk N. Comparison of the accuracy of machine learning algorithms for brain-computer interaction

TNTU Journal, 2021. Application of NeuroCom complexes.

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Savenko O. Development of software for neuromarketing based on AI and data science

TNTU Open Archive, 2020. EEG research based on XAI-MEDICA equipment.

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Tukaiev S. A. EEG frequencies pattern as brain signature of emotional burnout

International Journal of Physiology, 2018. Emotional burnout diagnosis.

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Yukhymenko O. V. Features of EEG patterns in individuals with different functional mobility of nervous processes

PhD Thesis. Taras Shevchenko National University of Kyiv, 2015. NeuroCom research.

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Shpenkov O. O. Changes in the electrical activity of the brain when listening to audio stimuli

Bulletin of Cherkasy University, 2014. EEG data analysis.

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Kryzhanovsky S. A. Correlation between activity efficiency and EEG parameters

Neurophysiology, 2009. Fundamental study.

SpiroCom - Spirometry

Equipment

Tyshchenko V., Singayevsky S. Enhancing respiratory function through Yoga and Pilates in women aged 45-50

Pedagogy of Physical Culture and Sports, 2024, 28(5), pp. 449-455. Study via SpiroCom.

Source

Feshchenko Yu. I. Monitoring of respiratory function in patients with COPD using digital complexes

Asthma and Allergy, 2020, No. 3. Clinical efficiency.

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Combined Studies

Kentesh O. P. Impact of autonomic dysfunction on the state and function of the endothelium in young individuals (CardioLab + ReoCom)

PhD Thesis. Uzhhorod National University, 2018.

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Spirina I. D. Psychophysiological aspects of adaptation and the functional state of the vascular system

Journal of Psychiatry and Psychopharmacotherapy, 2013. Comprehensive diagnostics.

Research collaboration: [email protected]

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